化工社化工社 化学情報印刷レポート · 研究参考用
Sodium Carbonate → 2-(4,4-Dimethyl-cyclohex-1-enyl)4-(6-methoxy-pyridin-3-yl)-phenylamine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Sodium Carbonate | HCID 10340 | — |
| 反応物 | 4,4-Dimethylcyclohexen-1-ylboronic acid | HCID 44119555 | — |
| 反応物 | HCID 58754809 | HCID 58754809 | — |
| 触媒 | HCID 178418397 | HCID 178418397 | — |
| 生成物 | 2-(4,4-Dimethyl-cyclohex-1-enyl)4-(6-methoxy-pyridin-3-yl)-phenylamine | HCID 58754885 | — |
反応手順
The title compound was prepared from 2-bromo-4-(6-methoxy-pyridin-3-yl)-phenylamine (as prepared in the previous step, 20 mg, 0.07 mmol), 4,4-dimethylcyclohexen-1-yl boronic acid (14 mg, 0.086 mmol), Pd(PPh3)4 (8.0 mg, 0.007 mmol) and 2M Na2CO3 (0.28 mL, 0.56 mmol) according to the procedure in Example 44, step (b) (16 mg, 76%). Mass spectrum (ESI, m/z): Calcd. for C20H24N2O, 309.1 (M+H), found 309.2.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07790724B2 |
| 出典データセット | uspto-grants-2010_09 |
| ORD ID | ord-2aac4646f3f74b749dba304d03d687aa |
| 出典メモ | uspto-grants-2010_09 |