Diisopropylethylamine → HCID 178424470, compound

Participants

Reaction Steps

The title compound was prepared from 2-(4,4-dimethyl-cyclohex-1-enyl)4-(1-trimethylstannanyl-1H-tetrazol-5-yl)-phenylamine (as prepared in the previous step, 150 mg, 0.347 mmol), potassium 4-cyano-1-(2-trimethylsilanyl-ethoxymethyl)-1H-imidazole-2-carboxylate (as prepared in Example 11, step (d), 148 mg, 0.480 mmol), PyBroP (259 mg, 0.555 mmol) and DIEA (151 μL, 0.867 mmol) according to the procedure in Example 11, step (f) (103 mg, 57%). Mass spectrum (ESI, m/z): Calcd. for C26H34N8O2Si, 519.2, found 519.1

Provenance & Evidence