3-Bromo-5-methylpyridine → HCID 67319709, compound

HRID 1711599Notes

Reaction equation

HRID 1711599 reaction equation
CC1(C)C(C)(C)OB([C:9]2[CH:14]=[CH:13][C:12]([C@@H:15]3[CH2:17][C@H:16]3[NH:18][S:19]([CH:22]([CH3:24])[CH3:23])(=[O:21])=[O:20])=[CH:11][CH:10]=2)O1.Br[C:27]1[CH:28]=[N:29][CH:30]=[C:31]([CH3:33])[CH:32]=1>>[CH3:33][C:31]1[CH:32]=[C:27]([C:9]2[CH:10]=[CH:11][C:12]([C@@H:15]3[CH2:17][C@H:16]3[NH:18][S:19]([CH:22]([CH3:23])[CH3:24])(=[O:20])=[O:21])=[CH:13][CH:14]=2)[CH:28]=[N:29][CH:30]=1

Participants

3

Reactant 2

HCID 8177133-Bromo-5-methylpyridineHCID 67319244HCID 67319244, compound2×

Product 1

HCID 67319709HCID 67319709, compound

Procedure

Example 11 was prepared from trans-N-{2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]cyclopropyl}-2-propanesulfonamide (Intermediate 8) (69 mg, 0.189 mmol) and 3-bromo-5-methylpyridine (65 mg, 0.378 mmol) according to a similar procedure as for Example 10.

Sources & evidence

ORD record
ord-699c9fb9481243cca69539c7ae15df5f
Source dataset
uspto-grants-2010_09
Patent number
US07790758B2

Reaction notes

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