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HRID1711750

反应详情

EQUATION

反应方程式

HRID 1711750 的结构方程式

REACTANTS

反应物

2
结构：Oc1cc(C(F)(F)F)cc(C(F)(F)F)c1
HCID67680

alpha,alpha,alpha,alpha',alpha',alpha'-Hexafluoro-3,5-xylenol

C8H4F6O

结构：CC(C)Oc1ccc(S(C)(=O)=O)cc1C(=O)N1CCC(OS(C)(=O)=O)C1
HCID58673069

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)Oc1ccc(S(C)(=O)=O)cc1C(=O)N1CCC(Oc2cc(C(F)(F)F)cc(C(F)(F)F)c2)C1
HCID58673067

未命名化合物

收率 19%

PROCEDURE

实验过程

Prepared in analogy to Example 3(c) from rac-methanesulfonic acid 1-(2-isopropoxy-5-methanesulfonyl-benzoyl)-pyrrolidin-3-yl ester (Example 14(a)) and 3,5-bis(trifluoromethyl)phenol. The crude material was purified by reversed phase HPLC (acetonitrile/water) to yield the title compound as an amorphous white solid (yield 19%). MS (m/e): 540.3 (M+H+, 100%).

WORKUP

后处理

  1. customThe crude material was purified by reversed phase HPLC (acetonitrile/water)