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HRID1711760

反应详情

EQUATION

反应方程式

HRID 1711760 的结构方程式

REACTANTS

反应物

2
结构：C[C@H](Oc1ccc(S(C)(=O)=O)cc1C(=O)O)C(F)(F)F
HCID58863351

未命名化合物

结构：OC1C=NC1
HCID68505089

未命名化合物

PRODUCTS

生成物

1
结构：C[C@H](Oc1ccc(S(C)(=O)=O)cc1C(=O)N1CC(O)C1)C(F)(F)F
HCID58673077

未命名化合物

收率 43%

PROCEDURE

实验过程

Prepared in analogy to Example 1 from 5-methanesulfonyl-2-((S)-2,2,2-trifluoro-1-methyl-ethoxy)-benzoic acid (Example A2(c)) and azetin-3-ol. The crude material was purified by flash chromatography (ethyl acetate/n-heptane) to yield the title compound as a white crystalline solid (yield 43%). MS (m/e): 367.9 (M+H+, 100%).

WORKUP

后处理

  1. customThe crude material was purified by flash chromatography (ethyl acetate/n-heptane)