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HRID1711767

反应详情

EQUATION

反应方程式

HRID 1711767 的结构方程式

REACTANTS

反应物

2
结构：FC(F)(F)c1ccc(OC2CCNC2)cc1
HCID18723127

3-[4-(Trifluoromethyl)phenoxy]pyrrolidine

C11H12F3NO

结构：CNS(=O)(=O)c1ccc(OC2CCCC2)c(C(=O)O)c1
HCID21100227

未命名化合物

PRODUCTS

生成物

1
结构：CNS(=O)(=O)c1ccc(OC2CCCC2)c(C(=O)N2CCC(Oc3ccc(C(F)(F)F)cc3)C2)c1
HCID11670727

未命名化合物

收率 11%

PROCEDURE

实验过程

Prepared in analogy to Example 1 from 2-cyclopentyloxy-5-methylsulfamoyl-benzoic acid (Example A5) and 3-(4-trifluoromethyl-phenoxy)-pyrrolidine (Example 25(b)). The crude material was purified by chromatography (methanol/dichloromethane) to yield the title compound as an off-white solid (yield 11%). MS (m/e): 513.5 (M+H+, 100%).

WORKUP

后处理

  1. customThe crude material was purified by chromatography (methanol/dichloromethane)