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HRID1711768

反应详情

EQUATION

反应方程式

HRID 1711768 的结构方程式

REACTANTS

反应物

2
结构：FC(F)(F)c1ccc(OC2CCNC2)cc1
HCID18723127

3-[4-(Trifluoromethyl)phenoxy]pyrrolidine

C11H12F3NO

结构：CC(C)Sc1ccc(S(C)(=O)=O)cc1C(=O)O
HCID21100252

2-[(1-Methylethyl)thio]-5-(methylsulfonyl)benzoic acid

C11H14O4S2

PRODUCTS

生成物

1
结构：CC(C)Sc1ccc(S(C)(=O)=O)cc1C(=O)N1CCC(Oc2ccc(C(F)(F)F)cc2)C1
HCID58673081

未命名化合物

收率 42%

PROCEDURE

实验过程

Prepared in analogy to Example 1 from 2-isopropylsulfanyl-5-methanesulfonyl-benzoic acid (Example A6) and 3-(4-trifluoromethyl-phenoxy)-pyrrolidine (Example 25(b)). The crude material was purified by chromatography (methanol/dichloromethane) to yield the title compound as a light brown solid (yield 42%). MS (m/e): 488.1 (M+H+, 100%).

WORKUP

后处理

  1. customThe crude material was purified by chromatography (methanol/dichloromethane)