HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Fluoro-3,5-dimethyl-2-nitrobenzene → HCID 56637722, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Fluoro-3,5-dimethyl-2-nitrobenzene | HCID 21875915 | — |
| Reactant | (3S)-2-Oxo-3-tert-butoxycarbonylamino-2,3,4,5-tetrahydro-1H-1,5-benzodiazepine-1-acetic acid methyl ester | HCID 54305289 | — |
| Reactant | HCID 56607952 | HCID 56607952 | — |
| Product | HCID 56637722 | HCID 56637722 | 93% |
Reaction Steps
(2S)-2-tert-Butoxycarbonylamino-3-(2-nitro-3,5-dimethylphenylamino)-propionic acid. Prepared by a method similar as described for 600a/103 (Step A), except 2-fluoro-4,6-dimethyl-nitrobenzene was used instead of 2-fluoronitrobenzene to give the desired compound in 93% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07790713B2 |
| Source dataset | uspto-grants-2010_09 |
| ORD ID | ord-22e88935bd9046fa891d3d63f313f916 |
| Source note | uspto-grants-2010_09 |