4-Fluorobenzoyl chloride → HCID 11602357, compound

HRID 1712026Notes

Reaction equation

HRID 1712026 reaction equation
[F:1][C:2]1[CH:10]=[CH:9][C:5]([C:6](Cl)=[O:7])=[CH:4][CH:3]=1.[CH3:11][O:12][C:13]1[CH:14]=[C:15]([C:19]2([OH:25])[CH2:24][CH2:23][CH2:22][NH:21][CH2:20]2)[CH:16]=[CH:17][CH:18]=1>>[F:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([N:21]2[CH2:22][CH2:23][CH2:24][C:19]([OH:25])([C:15]3[CH:16]=[CH:17][CH:18]=[C:13]([O:12][CH3:11])[CH:14]=3)[CH2:20]2)=[O:7])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 678794-Fluorobenzoyl chlorideHCID 116516763-(3-Methoxy-phenyl)-piperidine-3-ol

Product 1

HCID 11602357HCID 11602357, compound

Procedure

The compound of Example 3 was prepared according to the general preparation protocol A from 4-fluorobenzoyl chloride and 3-(3-methoxy-phenyl)-piperidine-3-ol.

Sources & evidence

ORD record
ord-5ce94eff69c24b65b1cfb37eaaff92ff
Source dataset
uspto-grants-2010_09
Patent number
US07790898B2

Reaction notes

Loading…