3,5-Difluorobenzoyl chloride → HCID 11709980, compound

HRID 1712029Notes

Reaction equation

HRID 1712029 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([CH:8]=[C:9]([F:11])[CH:10]=1)[C:5](Cl)=[O:6].[CH3:12][O:13][C:14]1[CH:15]=[C:16]([C:20]2([OH:26])[CH2:25][CH2:24][CH2:23][NH:22][CH2:21]2)[CH:17]=[CH:18][CH:19]=1>>[F:1][C:2]1[CH:3]=[C:4]([C:5]([N:22]2[CH2:23][CH2:24][CH2:25][C:20]([OH:26])([C:16]3[CH:17]=[CH:18][CH:19]=[C:14]([O:13][CH3:12])[CH:15]=3)[CH2:21]2)=[O:6])[CH:8]=[C:9]([F:11])[CH:10]=1

Participants

3

Reactant 2

HCID 1456003,5-Difluorobenzoyl chlorideHCID 116516763-(3-Methoxy-phenyl)-piperidine-3-ol

Product 1

HCID 11709980HCID 11709980, compound

Procedure

The compound of Example 6 was prepared according to the general preparation protocol A from 3,5-difluorobenzoyl chloride and 3-(3-methoxy-phenyl)-piperidine-3-ol.

Sources & evidence

ORD record
ord-f7fb0f1380904316be1620cc5ad25714
Source dataset
uspto-grants-2010_09
Patent number
US07790898B2

Reaction notes

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