Benzoyl chloride, 3,4-dichloro- → HCID 68506415, compound
Reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][C:10]=1[Cl:11])[C:5](Cl)=[O:6].[CH3:12][O:13][C:14]1[CH:15]=[C:16]([C:20]2([OH:26])[CH2:25][CH2:24][CH2:23][NH:22][CH2:21]2)[CH:17]=[CH:18][CH:19]=1>>[Cl:1][C:2]1[CH:3]=[C:4]([C:5]([N:22]2[CH2:23][CH2:24][CH2:25][C:20]([OH:26])([C:16]3[CH:17]=[CH:18][CH:19]=[C:14]([O:13][CH3:12])[CH:15]=3)[CH2:21]2)=[O:6])[CH:8]=[CH:9][C:10]=1[Cl:11]Participants
3
Procedure
The compound of Example 7 was prepared according to the general preparation protocol A from 3,4-dichlorobenzoyl chloride and 3-(3-methoxy-phenyl)-piperidine-3-ol.
Sources & evidence
- ORD record
- ord-da368ae6cdfd446d85e746af4b39b0d7
- Source dataset
- uspto-grants-2010_09
- Patent number
- US07790898B2
Reaction notes
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