3-Methylbenzoyl chloride → HCID 11602276, compound

HRID 1712031Notes

Reaction equation

HRID 1712031 reaction equation
[CH3:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][CH:10]=1)[C:5](Cl)=[O:6].[CH3:11][O:12][C:13]1[CH:14]=[C:15]([C:19]2([OH:25])[CH2:24][CH2:23][CH2:22][NH:21][CH2:20]2)[CH:16]=[CH:17][CH:18]=1>>[OH:25][C:19]1([C:15]2[CH:16]=[CH:17][CH:18]=[C:13]([O:12][CH3:11])[CH:14]=2)[CH2:24][CH2:23][CH2:22][N:21]([C:5]([C:4]2[CH:3]=[C:2]([CH3:1])[CH:10]=[CH:9][CH:8]=2)=[O:6])[CH2:20]1

Participants

3

Reactant 2

HCID 743753-Methylbenzoyl chlorideHCID 116516763-(3-Methoxy-phenyl)-piperidine-3-ol

Product 1

HCID 11602276HCID 11602276, compound

Procedure

The compound of Example 8 was prepared according to the general preparation protocol A from 3-methylbenzoyl chloride and 3-(3-methoxy-phenyl)-piperidine-3-ol.

Sources & evidence

ORD record
ord-e96249ea238a420ab785116cab86e202
Source dataset
uspto-grants-2010_09
Patent number
US07790898B2

Reaction notes

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