4-Methylbenzoyl Chloride → HCID 11515357, compound

HRID 1712032Notes

Reaction equation

HRID 1712032 reaction equation
[CH3:1][C:2]1[CH:10]=[CH:9][C:5]([C:6](Cl)=[O:7])=[CH:4][CH:3]=1.[CH3:11][O:12][C:13]1[CH:14]=[C:15]([C:19]2([OH:25])[CH2:24][CH2:23][CH2:22][NH:21][CH2:20]2)[CH:16]=[CH:17][CH:18]=1>>[OH:25][C:19]1([C:15]2[CH:16]=[CH:17][CH:18]=[C:13]([O:12][CH3:11])[CH:14]=2)[CH2:24][CH2:23][CH2:22][N:21]([C:6]([C:5]2[CH:9]=[CH:10][C:2]([CH3:1])=[CH:3][CH:4]=2)=[O:7])[CH2:20]1

Participants

3

Reactant 2

HCID 134054-Methylbenzoyl ChlorideHCID 116516763-(3-Methoxy-phenyl)-piperidine-3-ol

Product 1

HCID 11515357HCID 11515357, compound

Procedure

The compound of Example 9 was prepared according to the general preparation protocol A from 4-methylbenzoyl chloride and 3-(3-methoxy-phenyl)-piperidine-3-ol.

Sources & evidence

ORD record
ord-5942d15428b8430282b50a75c3416a95
Source dataset
uspto-grants-2010_09
Patent number
US07790898B2

Reaction notes

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