4-Cyanobenzoyl chloride → HCID 68504219, compound

HRID 1712034Notes

Reaction equation

HRID 1712034 reaction equation
[C:1]([C:3]1[CH:11]=[CH:10][C:6]([C:7](Cl)=[O:8])=[CH:5][CH:4]=1)#[N:2].[CH3:12][O:13][C:14]1[CH:15]=[C:16]([C:20]2([OH:26])[CH2:25][CH2:24][CH2:23][NH:22][CH2:21]2)[CH:17]=[CH:18][CH:19]=1>>[OH:26][C:20]1([C:16]2[CH:17]=[CH:18][CH:19]=[C:14]([O:13][CH3:12])[CH:15]=2)[CH2:25][CH2:24][CH2:23][N:22]([C:7]([C:6]2[CH:10]=[CH:11][C:3]([C:1]#[N:2])=[CH:4][CH:5]=2)=[O:8])[CH2:21]1

Participants

3

Reactant 2

HCID 801724-Cyanobenzoyl chlorideHCID 116516763-(3-Methoxy-phenyl)-piperidine-3-ol

Product 1

HCID 68504219HCID 68504219, compound

Procedure

The compound of Example 12 was prepared according to the general preparation protocol A from 4-cyanobenzoyl chloride and 3-(3-methoxy-phenyl)-piperidine-3-ol.

Sources & evidence

ORD record
ord-88ec2ceb27b84a899fbeb469bf9c1fa9
Source dataset
uspto-grants-2010_09
Patent number
US07790898B2

Reaction notes

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