2,6-Difluorobenzoyl chloride → HCID 11551974, compound

HRID 1712044Notes

Reaction equation

HRID 1712044 reaction equation
[F:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]([F:11])[C:3]=1[C:4](Cl)=[O:5].[CH3:12][O:13][C:14]1[CH:15]=[C:16]([C:20]2([OH:26])[CH2:25][CH2:24][CH2:23][NH:22][CH2:21]2)[CH:17]=[CH:18][CH:19]=1>>[F:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]([F:11])[C:3]=1[C:4]([N:22]1[CH2:23][CH2:24][CH2:25][C:20]([OH:26])([C:16]2[CH:17]=[CH:18][CH:19]=[C:14]([O:13][CH3:12])[CH:15]=2)[CH2:21]1)=[O:5]

Participants

3

Reactant 2

HCID 874382,6-Difluorobenzoyl chlorideHCID 116516763-(3-Methoxy-phenyl)-piperidine-3-ol

Product 1

HCID 11551974HCID 11551974, compound

Procedure

The compound of Example 23 was prepared according to the general preparation protocol A from 2,6-diflourobenzoyl chloride and 3-(3-methoxy-phenyl)-piperidine-3-ol.

Sources & evidence

ORD record
ord-5cd9236c32de442394b5561ec2d10335
Source dataset
uspto-grants-2010_09
Patent number
US07790898B2

Reaction notes

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