3,5-Bis(trifluoromethyl)benzoyl chloride → HCID 11597505, compound

HRID 1712046Notes

Reaction equation

HRID 1712046 reaction equation
[F:1][C:2]([F:17])([F:16])[C:3]1[CH:4]=[C:5]([CH:9]=[C:10]([C:12]([F:15])([F:14])[F:13])[CH:11]=1)[C:6](Cl)=[O:7].[CH3:18][O:19][C:20]1[CH:21]=[C:22]([C:26]2([OH:32])[CH2:31][CH2:30][CH2:29][NH:28][CH2:27]2)[CH:23]=[CH:24][CH:25]=1>>[F:1][C:2]([F:17])([F:16])[C:3]1[CH:4]=[C:5]([C:6]([N:28]2[CH2:29][CH2:30][CH2:31][C:26]([OH:32])([C:22]3[CH:23]=[CH:24][CH:25]=[C:20]([O:19][CH3:18])[CH:21]=3)[CH2:27]2)=[O:7])[CH:9]=[C:10]([C:12]([F:15])([F:14])[F:13])[CH:11]=1

Participants

3

Reactant 2

HCID 1018563,5-Bis(trifluoromethyl)benzoyl chlorideHCID 116516763-(3-Methoxy-phenyl)-piperidine-3-ol

Product 1

HCID 11597505HCID 11597505, compound

Procedure

The compound of Example 25 was prepared according to the general preparation protocol A from 3,5-bis(trifluoromethyl)benzoyl chloride and 3-(3-methoxy-phenyl)-piperidine-3-ol.

Sources & evidence

ORD record
ord-2c2422cd2b53468496d120575d6657c7
Source dataset
uspto-grants-2010_09
Patent number
US07790898B2

Reaction notes

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