4-Fluorobenzoyl chloride → HCID 11609363, compound

HRID 1712053Notes

Reaction equation

HRID 1712053 reaction equation
[F:1][C:2]1[CH:10]=[CH:9][C:5]([C:6](Cl)=[O:7])=[CH:4][CH:3]=1.[OH:11][C:12]1[CH:13]=[C:14]([C:18]2([OH:24])[CH2:23][CH2:22][CH2:21][NH:20][CH2:19]2)[CH:15]=[CH:16][CH:17]=1>>[F:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([N:20]2[CH2:21][CH2:22][CH2:23][C:18]([OH:24])([C:14]3[CH:15]=[CH:16][CH:17]=[C:12]([OH:11])[CH:13]=3)[CH2:19]2)=[O:7])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 678794-Fluorobenzoyl chlorideHCID 68505643HCID 68505643, compound

Product 1

HCID 11609363HCID 11609363, compound

Procedure

The compound of Example 55 was prepared according to the general preparation protocol A from 4-fluorobenzoyl chloride and 3-(3-hydroxyphenyl)-piperidine-3-ol.

Sources & evidence

ORD record
ord-02dd2f5f304140c7b0e6720c8153dfa7
Source dataset
uspto-grants-2010_09
Patent number
US07790898B2

Reaction notes

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