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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1712167Generated: October 25, 2026

N,N-Diethyl-1,4-butanediamine → 5-[3-(4-Diethylamino-butyl)-ureido]-3-(2,3,6-trifluoro-4-methyl-benzyloxy)-isothiazole-4-carboxylic Acid Amide

https://huagongshe.com/reaction/1712167

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN,N-Diethyl-1,4-butanediamineHCID 117976—
Reactant[4-Carbamoyl-3-(2,3,6-trifluoro-4-methyl-benzyloxy)-isothiazol-5-yl]-carbamic acid phenyl esterHCID 54053016—
Product5-[3-(4-Diethylamino-butyl)-ureido]-3-(2,3,6-trifluoro-4-methyl-benzyloxy)-isothiazole-4-carboxylic Acid AmideHCID 11705804—

Reaction Steps

The title compound was prepared from [4-carbamoyl-3-(2,3,6-trifluoro-4-methyl-benzyloxy)-isothiazol-5-yl]-carbamic acid phenyl ester and N,N-diethyl-butane-1,4-diamine by the procedure analogous to Example 1. MS (APCI, m/z): 488 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07790902B2
Source datasetuspto-grants-2010_09
ORD IDord-8ab16d9e380041348d2d8f954bb38686
Source noteuspto-grants-2010_09