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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 171217Generated: November 2, 2026

Tetrahydrofuran → 4-[2-Hydroxy-1-(3-trifluoromethyl-phenyl)-ethyl]-piperazine-1-carboxylic acid tert-butyl ester

https://huagongshe.com/reaction/171217

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantLithium ionHCID 28486—
ReactantAluminum CationHCID 104727—
ReactantHydrideHCID 166653—
Reactant4-[Ethoxycarbonyl-(3-trifluoromethyl-phenyl)-methyl]-piperazine-1-carboxylic acid tert-butyl esterHCID 67151962—
Product4-[2-Hydroxy-1-(3-trifluoromethyl-phenyl)-ethyl]-piperazine-1-carboxylic acid tert-butyl esterHCID 59011973—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-fe35308d38314c4fb4d7b4090f06630d
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)