HuagongsheHuagongshe Chemistry Print Report · For research reference only
(4-chloro-2-Methylphenoxy)acetic acid → 2-(2-Benzenesulfinylmethyl-benzoimidazol-1-yl)-2,N-dicyclohexyl-acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (4-chloro-2-Methylphenoxy)acetic acid | HCID 7204 | — |
| Reactant | (phenylsulfinyl)acetic acid | HCID 233599 | — |
| Reactant | N-(tert-Butoxycarbonyl)-1,2-phenylenediamine | HCID 676311 | — |
| Reactant | N1-(tert-Butoxycarbonyl)-4-fluoro-1,2-phenylenediamine | HCID 24688763 | — |
| Product | 2-(2-Benzenesulfinylmethyl-benzoimidazol-1-yl)-2,N-dicyclohexyl-acetamide | HCID 42606154 | — |
Reaction Steps
The title compound was prepared in analogy to Example 1,replacing (2-amino-4-fluoro-phenyl)-carbamic acid tert-butyl ester (Intermediate A) with (2-amino-phenyl)-carbamic acid tert-butyl ester ([CAS RN 146651-75-4]) and (4-chloro-2-methyl-phenoxy)-acetic acid with benzenesulfinyl-acetic acid ([CAS RN 3959-08-8]). MS (ISP): 478.1 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07790904B2 |
| Source dataset | uspto-grants-2010_09 |
| ORD ID | ord-6732613f0ff14101a6f80c0fea571c51 |
| Source note | uspto-grants-2010_09 |