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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 171231Generated: October 25, 2026

Hydrochloric Acid → Tert-butyl 2-[(1-chloro-4-hydroxyisoquinoline-3-carbonyl)amino]-3-[(2-methylpropan-2-yl)oxy]propanoate

https://huagongshe.com/reaction/171231

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantDichloromethaneHCID 6344—
ReactantDiisopropylethylamineHCID 81531—
Reactant(S)-tert-Butyl 2-amino-3-tert-butoxypropanoateHCID 424370—
Reactant1-Chloro-4-hydroxyisoquinoline-3-carboxylic acidHCID 11020520—
ProductTert-butyl 2-[(1-chloro-4-hydroxyisoquinoline-3-carbonyl)amino]-3-[(2-methylpropan-2-yl)oxy]propanoateHCID 87120367—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-890968c49c4e4247aa3e54a66418a966
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)