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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1712367Generated: October 30, 2026

1-(3-bromopropoxy)-2-chlorobenzene → HCID 68504254, compound

https://huagongshe.com/reaction/1712367

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(3-bromopropoxy)-2-chlorobenzeneHCID 2734933—
ReactantTert-butyl 4-(4-hydroxyphenyl)-3-[1-(3-methoxypropyl)-2-oxo-1,2,3,4-tetrahydroquinolin-7-ylmethoxy]piperidine-1-carboxylateHCID 68501561—
ProductHCID 68504254HCID 68504254—

Reaction Steps

Analogously to Method I, 0.100 g of tert-butyl 4-(4-hydroxyphenyl)-3-[1-(3-methoxypropyl)-2-oxo-1,2,3,4-tetrahydroquinolin-7-ylmethoxy]piperidine-1-carboxylate (Example 44d) and 0.062 g of 1-(3-bromopropoxy)-2-chlorobenzene are used to prepare the title compound. Rf=0.27 (2:1 EtOAc-heptane); Rt=6.07.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07790715B2
Source datasetuspto-grants-2010_09
ORD IDord-cdb7bd2cac8943a6a8f102a811298b9f
Source noteuspto-grants-2010_09