1,4-Dibromobutane → 2-(4-Bromobutoxy)-1-methoxy-3-methylbenzene

HRID 1712373Notes

Reaction equation

HRID 1712373 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][CH:6]=[C:5]([CH3:9])[C:4]=1[OH:10].[Br:11][CH2:12][CH2:13][CH2:14][CH2:15]Br>>[Br:11][CH2:12][CH2:13][CH2:14][CH2:15][O:10][C:4]1[C:5]([CH3:9])=[CH:6][CH:7]=[CH:8][C:3]=1[O:2][CH3:1]

Participants

3

Reactant 2

HCID 80561,4-DibromobutaneHCID 761732-Methoxy-6-methylphenol

Product 1

HCID 685017942-(4-Bromobutoxy)-1-methoxy-3-methylbenzene

Procedure

Analogously to Example 50b, 2.50 g of 2-methoxy-6-methylphenol and 2.67 ml of 1,4-dibromobutane are used to prepare the title compound. Rf=0.58 (1:1 EtOAc-heptane); Rt=5.28.

Sources & evidence

ORD record
ord-78d085ac9f3042919a805420b8bec61d
Source dataset
uspto-grants-2010_09
Patent number
US07790715B2

Reaction notes

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