HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 68505258, compound → tert-Butyl 3-{2-[2-(2-acetylaminoethyl)-3-methylphenoxy]ethoxy}-4-{4-[3-(2-methoxybenzyloxy)propoxy]phenyl}piperidine-1-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 68505258 | HCID 68505258 | — |
| Reactant | Tert-butyl 4-{4-[3-(2-methoxybenzyloxy)propoxy]phenyl}-3-[2-(toluene-4-sulphonyloxy)ethoxy]piperidine-1-carboxylate | HCID 86609984 | — |
| Product | tert-Butyl 3-{2-[2-(2-acetylaminoethyl)-3-methylphenoxy]ethoxy}-4-{4-[3-(2-methoxybenzyloxy)propoxy]phenyl}piperidine-1-carboxylate | HCID 68499803 | — |
Reaction Steps
Analogously to Method G, 0.44 g of tert-butyl 4-{4-[3-(2-methoxybenzyloxy)propoxy]phenyl}-3-[2-(toluene-4-sulphonyloxy)ethoxy]piperidine-1-carboxylate (Example 14b) and 0.25 g of N-[2-(2-hydroxy-6-methylphenyl)ethyl]acetamide are reacted. The title compound is obtained as a colourless oil. Rf=0.50 (EtOAc); Rt=5.77.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07790715B2 |
| Source dataset | uspto-grants-2010_09 |
| ORD ID | ord-60d0d63c841a49b688ea33f0b60f967d |
| Source note | uspto-grants-2010_09 |