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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1712446Generated: November 1, 2026

(3S,4S)-tert-Butyl 3-hydroxy-4-(4-hydroxyphenyl)piperidine-1-carboxylate → HCID 68499821, compound

https://huagongshe.com/reaction/1712446

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(3S,4S)-tert-Butyl 3-hydroxy-4-(4-hydroxyphenyl)piperidine-1-carboxylateHCID 21713087—
Reactant1-(3-Bromopropoxy)-3-fluorobenzeneHCID 23294433—
ProductHCID 68499821HCID 68499821—

Reaction Steps

Analogously to Method I, 0.750 g of tert-butyl 3-hydroxy-4-(4-hydroxyphenyl)piperidine-1-carboxylate and 0.723 g of 1-(3-bromopropoxy-3-fluorobenzene are reacted. The title compound is obtained as a slightly yellowish oil. Rf=0.30 (1:2 EtOAc-heptane); Rt=5.29.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07790715B2
Source datasetuspto-grants-2010_09
ORD IDord-ca8bb7e4120f4bec92e72af2da94cd87
Source noteuspto-grants-2010_09