1-Chloro-3-methoxypropane → 1-Ethoxy-2-(3-methoxypropoxy)-4-methylbenzene

HRID 1712459Notes

Reaction equation

HRID 1712459 reaction equation
[CH2:1]([O:3][C:4]1[CH:9]=[CH:8][C:7]([CH3:10])=[CH:6][C:5]=1[OH:11])[CH3:2].Cl[CH2:13][CH2:14][CH2:15][O:16][CH3:17]>>[CH2:1]([O:3][C:4]1[CH:9]=[CH:8][C:7]([CH3:10])=[CH:6][C:5]=1[O:11][CH2:13][CH2:14][CH2:15][O:16][CH3:17])[CH3:2]

Participants

3

Reactant 2

HCID 1189271-Chloro-3-methoxypropaneHCID 122571232-Ethoxy-5-methylphenol

Product 1

HCID 592240741-Ethoxy-2-(3-methoxypropoxy)-4-methylbenzene

Procedure

Analogously to Method F, 5.05 g of 2-ethoxy-5-methylphenol and 4.03 g of 1-chloro-3-methoxypropane are reacted. The title compound is obtained as a slightly orange oil. Rf=0.32 (1:4 EtOAc-heptane); Rt=4.60

Sources & evidence

ORD record
ord-6d574666e20d46d3ab5e71c4a92868eb
Source dataset
uspto-grants-2010_09
Patent number
US07790715B2

Reaction notes

Loading…