HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-(chloromethyl)-4-(3-methoxypropyl)-2H-benzo[b][1,4]oxazin-3(4H)-one → HCID 68501239, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-(chloromethyl)-4-(3-methoxypropyl)-2H-benzo[b][1,4]oxazin-3(4H)-one | HCID 46835223 | — |
| Reactant | HCID 68503000 | HCID 68503000 | — |
| Product | HCID 68501239 | HCID 68501239 | — |
Reaction Steps
Analogously to Method D, 0.540 g of tert-butyl 4-{4-[3-(3,4-difluorophenoxy)propoxy]phenyl}-3-hydroxypiperidine-1-carboxylate and 0.353 g of 6-chloromethyl-4-(3-methoxypropyl)-4H-benzo[1,4]oxazin-3-one (Example 2a) are reacted. The title compound is obtained as a yellowish oil. Rf=0.26 (1:1 EtOAc-heptane); Rt=5.98.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07790715B2 |
| Source dataset | uspto-grants-2010_09 |
| ORD ID | ord-ec45d3832c5e4960bc257b8e8c740461 |
| Source note | uspto-grants-2010_09 |