Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1712504Generated: November 1, 2026

HCID 68500610, compound → HCID 68501828, compound

https://huagongshe.com/reaction/1712504

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 68500610HCID 68500610—
Reactant6-chloromethyl-4-(2-triisopropylsilanyloxyethyl)-4H-benzo[1,4]oxazin-3-oneHCID 68504773—
ProductHCID 68501828HCID 68501828—

Reaction Steps

Analogously to Method D, 1.34 g of benzyl 4-{4-[3-(2,5-difluorophenoxy)propoxy]phenyl}-3-hydroxypiperidine-1-carboxylate and 1.43 g of 6-chloromethyl-4-(2-triisopropylsilanyloxyethyl)-4H-benzo[1,4]oxazin-3-one are reacted. The title compound is obtained as a slightly yellowish oil. Rf=0.55 (1:1 EtOAc-heptane); Rt=7.03.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07790715B2
Source datasetuspto-grants-2010_09
ORD IDord-11d13b13d0924822ac7119b6a065e800
Source noteuspto-grants-2010_09