1-(3,5-Dichloropyridin-2-yl)piperazine → 4-Bromo-2-[4-(3,5-dichloropyridin-2-yl)piperazin-1-yl]-6-trifluoromethyl-1H-benzoimidazole
Reaction equation
[Br:15][c:16]1[cH:17][c:18]([C:26]([F:27])([F:28])[F:29])[cH:19][c:20]2[nH:21][c:22]([Cl:25])[n:23][c:24]12.[Cl:1][c:2]1[c:3]([N:9]2[CH2:10][CH2:11][NH:12][CH2:13][CH2:14]2)[n:4][cH:5][c:6]([Cl:8])[cH:7]1>>[Cl:1][c:2]1[c:3]([N:9]2[CH2:10][CH2:11][N:12]([c:22]3[nH:21][c:20]4[cH:19][c:18]([C:26]([F:27])([F:28])[F:29])[cH:17][c:16]([Br:15])[c:24]4[n:23]3)[CH2:13][CH2:14]2)[n:4][cH:5][c:6]([Cl:8])[cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-f3c3f76941d04c14a0ee8b6b17bad01c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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