2-Bromomethylnaphthalene → HCID 17902008, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 2-(bromomethyl)naphthalene (0.500 g) in N,N-dimethylformamide (11 mL) was added potassium phthalimide (0.461 g), and the resulting mixture was stirred at 50° C. for 2 hours. The reaction mixture was partitioned between ethyl acetate (50 mL) and water (15 mL). The organic layer was washed successively with water (15 mL×2) and brine (15 mL), dried over anhydrous sodium sulfate and concentrated under reduced pressure to give the title compound (0.380 g).

Provenance & Evidence