Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1713301Generated: October 31, 2026

4-(tert-Butoxycarbonylaminomethyl)phenylboronic acid, pinacol ester → Tert-butyl n-(3'-benzyloxy-5'-dimethylcarbamoylbiphenyl-4-ylmethyl)carbamate

https://huagongshe.com/reaction/1713301

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(tert-Butoxycarbonylaminomethyl)phenylboronic acid, pinacol esterHCID 3415442—
Reactant3-Benzyloxy-5-hydroxy-N,N-dimethylbenzamideHCID 67456467—
ProductTert-butyl n-(3'-benzyloxy-5'-dimethylcarbamoylbiphenyl-4-ylmethyl)carbamateHCID 67454928—

Reaction Steps

The title compound was prepared in a similar manner to that described in Reference Example 58 using 3-benzyloxy-5-hydroxy-N,N-dimethylbenzamide instead of 4-hydroxy-3-methoxybenzaldehyde and tert-butyl N-[4-(4,4,5,5-tetramethyl-[1,3,2]-dioxaborolane-2-yl)bezyl]carbamate instead of phenylboronic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07795236B2
Source datasetuspto-grants-2010_09
ORD IDord-57ace74f7efb4a0ab833679c0cc42273
Source noteuspto-grants-2010_09