2-(Ethylamino)ethanol → HCID 67541274, compound

HRID 1713307Notes

Reaction equation

HRID 1713307 reaction equation
Cl[CH2:2][CH2:3][CH2:4][O:5][C:6]1[CH:11]=[C:10]([CH2:12][NH:13][C:14](=[O:20])[O:15][C:16]([CH3:19])([CH3:18])[CH3:17])[CH:9]=[CH:8][C:7]=1[C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1.[CH2:27]([NH:29][CH2:30][CH2:31][OH:32])[CH3:28]>>[CH2:27]([N:29]([CH2:2][CH2:3][CH2:4][O:5][C:6]1[CH:11]=[C:10]([CH2:12][NH:13][C:14](=[O:20])[O:15][C:16]([CH3:19])([CH3:18])[CH3:17])[CH:9]=[CH:8][C:7]=1[C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1)[CH2:30][CH2:31][OH:32])[CH3:28]

Participants

3

Reactant 2

HCID 80722-(Ethylamino)ethanolHCID 67457175HCID 67457175, compound

Product 1

HCID 67541274HCID 67541274, compound

Procedure

The title compound was prepared in a similar manner to that described in Reference Example 139 using tert-butyl N-[2-(3-chloropropoxy)biphenyl-4-ylmethyl]carbamate instead of 3-(3-chloropropoxy)-4-phenylbenzonitrile and 2-ethylaminoethanol instead of pyrrolidine.

Sources & evidence

ORD record
ord-d5f5d550a551454daccd954bc73d9dc0
Source dataset
uspto-grants-2010_09
Patent number
US07795236B2

Reaction notes

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