N-3-Bromopropylphthalimide → HCID 67457659, compound

HRID 1713313Notes

Reaction equation

HRID 1713313 reaction equation
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:13]=[CH:12][CH:11]=[C:10]([CH2:14][NH:15][C:16](=[O:22])[O:17][C:18]([CH3:21])([CH3:20])[CH3:19])[CH:9]=2)=[CH:4][CH:3]=1.BrCCCN1[C:31](=[O:32])[C:30]2=[CH:33][CH:34]=[CH:35][CH:36]=[C:29]2C1=O>>[CH2:31]([O:32][C:16]([NH:15][CH2:14][CH2:10][CH2:9][O:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[CH:13]=[CH:12][CH:11]=[C:10]([CH2:14][NH:15][C:16](=[O:22])[O:17][C:18]([CH3:19])([CH3:21])[CH3:20])[CH:9]=2)=[CH:6][CH:7]=1)=[O:17])[C:30]1[CH:29]=[CH:36][CH:35]=[CH:34][CH:33]=1

Participants

3

Reactant 2

HCID 21611N-3-BromopropylphthalimideHCID 58907511HCID 58907511, compound

Product 1

HCID 67457659HCID 67457659, compound

Procedure

The title compound was prepared in a similar manner to that described in Reference Example 31 using tert-butyl N-(4′-hydroxybiphenyl-3-ylmethyl)carbamate instead of tert-butyl N-(3′-hydroxybiphenyl-4-ylmethyl)carbamate and N-(3-bromopropyl)phthalimide instead of N-(4-bromobutyl)-phthalimide.

Sources & evidence

ORD record
ord-7cabb5963a51462c8cd18a002a03bd5c
Source dataset
uspto-grants-2010_09
Patent number
US07795236B2

Reaction notes

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