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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1713317Generated: November 2, 2026

Benzene, 1-bromo-3-nitro- → (3'-Nitro[1,1'-biphenyl]-4-yl)methanol

https://huagongshe.com/reaction/1713317

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzene, 1-bromo-3-nitro-HCID 11457—
Reactant4-(Hydroxymethyl)benzeneboronic acidHCID 2734706—
Product(3'-Nitro[1,1'-biphenyl]-4-yl)methanolHCID 23005013—

Reaction Steps

The title compound was prepared in a similar manner to that described in Reference Example 2 using 1-bromo-3-nitrobenzene instead of tert-butyl N-(4-bromobenzyl) carbamate and 4-hydroxymethylphenylboronic acid instead of 3-benzyloxyphenylboronic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07795236B2
Source datasetuspto-grants-2010_09
ORD IDord-f6c875c5fa874ed3a9a19fc2c5a6dd08
Source noteuspto-grants-2010_09