Methanol → HCID 59460409, compound

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Reaction Steps

A mixture of 8-{3-[3-(N-benzyloxycarbonyl-N-ethyl-amino)propoxy]biphenyl-4-ylmethylamino}adenosine (0.18 g) and 10% palladium on carbon (43.8 wt % H2O, 0.21 g) in methanol (5.3 mL) was stirred at room temperature for 24 hours under a hydrogen atmosphere. The insoluble material was filtered out and the filtrate was concentrated under reduced pressure. The residue was purified by column chromatography on amino-propylated silica gel (eluent: dichloromethane/methanol=8/1 to 6/1) to give the title compound (0.12 g).

Provenance & Evidence