HCID 11263973, compound → HCID 59463790, compound

Participants

Reaction Steps

To a chilled (0° C.) solution of 3 g (16 mmol) of (4-methylchroman-4-yl)acetaldehyde in 30 mL of anhydrous tetrahydrofuran was added 0.3 g (8 mmol) LiAlH4 in one portion. The mixture was then warmed to room temperature and stirred for 30 minutes. The reaction was cooled to 0° C. and carefully quenched with a few drops of water. The reaction was warmed to room temperature, dried over magnesium sulfate, filtered through diamataceous earth and concentrated in vacuo to afford 2.8 g (93%) of 2-(4-methylchroman-4-yl)ethanol as an oil.

Provenance & Evidence