HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxalyl chloride → 6-Dimethylsulfamoyl-pyrazolo[1,5-a]pyridine-3-carbonyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | 6-(N,N-Dimethylsulfamoyl)pyrazolo[1,5-a]pyridine-3-carboxylic acid | HCID 68503874 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | 6-Dimethylsulfamoyl-pyrazolo[1,5-a]pyridine-3-carbonyl chloride | HCID 86625117 | — |
Reaction Steps
6-Dimethylsulfamoyl-pyrazolo[1,5-a]pyridine-3-carboxylic acid (200 mg, 0.57 mmol) are dissolved in 4 ml chloroform and oxalylchloride (97 μl, 1.14 mmol; Fluka) are added. The reaction is refluxed for 3 hours and then volatiles are removed under reduced pressure. The crude product is directly used in the next step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07795273B2 |
| Source dataset | uspto-grants-2010_09 |
| ORD ID | ord-5694a6fc30974663b948688be9fd5858 |
| Source note | uspto-grants-2010_09 |