Water → HCID 23122083, compound

Participants

Reaction Steps

Methyl α-[[(tetrahydro-3-oxo-1,1-diphenyl-3H-oxazolo[3,4-a]pyrazin-7(1H)-yl)carbonyl]amino]benzeneacetate (0.15 g, 0.31 mmol) was dissolved in tetrahydrofuran (2 mL). Lithium borohydride (14 mg, 0.64 mmol) was added thereto, and the mixture was stirred at room temperature for 2 hours. To the reaction solution was added water, and the mixture was extracted with ethyl acetate. The organic layer was washed with water, and then concentrated under reduced pressure. The residue was purified with silica gel column chromatography (ethyl acetate) and powder was formed from hexane to obtain the title compound (0.13 g, yield 90%).

Provenance & Evidence