Potassium Sodium Tartrate → HCID 68792359, compound

Participants

Reaction Conditions

Reaction Steps

Methyl 2-((2S,3R,4S,5R,6R)-3,4,5-tris(benzyloxy)-6-(benzyloxymethyl)-2-methoxytetrahydro-2H-pyran-2-yl)acetate (7) (0.48 g, 0.77 mmol) was dissolved in THF (8 mL) under an atmosphere of Ar and cooled to 0° C. DIBAL-H (2 mL of a 20% solution in toluene) was added dropwise. The reaction mixture was stirred at room temperature for 0.75 h, then cooled again to 0° C. and stirred with Rochelle's salt for 2 hours. The mixture was extracted with Et2O (3×). The organic layers were combined, washed with H2O (1×), dried (Na2SO4) and concentrated to a syrup (0.46 g, 100%). LC/MS 98.5% (ELSD) tR=3.10 min, calcd for C37H42O7: 598.29, found 621.3 (M+Na)+.

Provenance & Evidence