HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Methoxyphenylacetaldehyde → [5-(4-Methoxy-phenyl)-thiazol-2-yl]-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Methoxyphenylacetaldehyde | HCID 79782 | — |
| Reactant | Flt-3 Inhibitor III | HCID 11772958 | — |
| Solvent | Dichloromethane methanol | HCID 21226129 | — |
| Product | [5-(4-Methoxy-phenyl)-thiazol-2-yl]-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-amine | HCID 11188635 | — |
Reaction Steps
The title compound is prepared as described in Example 1 for (5-phenyl-thiazol-2-yl)-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-amine but using (4-methoxy-phenyl)-acetaldehyde. Title compound: ES-MS: 396.0 [M+H]+; single peak at tR=6.36 min (System 1); R4=0.28 (CH2Cl2/MeOH, 80/20).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07795288B2 |
| Source dataset | uspto-grants-2010_09 |
| ORD ID | ord-ab3f769150d64c4c96a4f675c00d5809 |
| Source note | uspto-grants-2010_09 |