HuagongsheHuagongshe Chemistry Print Report · For research reference only
{5-[4-(3-Dimethylamino-propoxy)-phenyl]-thiazol-2-yl}phenyl-amine → [4-(3-Dimethylamino-propoxy)-phenyl]-(5-thiophen-3-yl-thiazol-2-yl)-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | {5-[4-(3-Dimethylamino-propoxy)-phenyl]-thiazol-2-yl}phenyl-amine | HCID 11245147 | — |
| Reactant | 4-(5-Thiophen-3-yl-thiazol-2-yl-amino)-phenol | HCID 11288835 | — |
| Solvent | Dichloromethane methanol | HCID 21226129 | — |
| Product | [4-(3-Dimethylamino-propoxy)-phenyl]-(5-thiophen-3-yl-thiazol-2-yl)-amine | HCID 11405705 | — |
Reaction Steps
The title compound is prepared as described in Example 8 for {5-[4-(3-dimethylamino-propoxy)-phenyl]-thiazol-2-yl}phenyl-amine but starting from 4-(5-thiophen-3-yl-thiazol-2-yl-amino)-phenol (Example 12). Title compound: ES-MS: 360.0 [M+H]+; single peak at tR=6.16 min (System 1); Rf=0.12 (CH2Cl2/MeOH, 85/15).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07795288B2 |
| Source dataset | uspto-grants-2010_09 |
| ORD ID | ord-3acdd498a2dc4dac8356a25ccf5bf1d4 |
| Source note | uspto-grants-2010_09 |