反应详情

The title compound is prepared as described in Example 8 for {5-[4-(3-dimethylamino-propoxy)-phenyl]-thiazol-2-yl}-phenyl-amine but starting from 4-(5-thiophen-3-yl-thiazol-2-yl-amino)-phenol (Example 12) and using 1-(2-chloroethyl)-piperidine hydrochloride. Title compound: ES-MS: 386.0 [M+H]+; single peak at tR=6.26 min (System 1); Rf=0.36 (CH2Cl2/MeOH, 80/20).

1. customThe title compound is prepared