HCID 67394150, compound → HCID 67392365, compound

Participants

Reaction Steps

20 mg of 10% palladium on activated carbon is added to 210 mg (0.65 mmol) of 5-methoxy-2-(morpholin-4-ylcarbonyl)-4-nitro-1,3-benzothiazole in solution in 10 ml of methanol. The reaction medium is then placed under stirring under a hydrogen atmosphere for 18 hours. The catalyst is then filtered out and the solvent is evaporated off. 173 mg of the expected product (gross yield=91%) is obtained in the form of a yellow oil and is used in the following stage without other purification.

Provenance & Evidence