Methanol → HCID 11686114, compound

Participants

Reaction Conditions

Reaction Steps

81 μl (0.73 mmol; 2 eq.) of N,N-dimethylethylenediamine is added to 200 mg of N,N′-(oxydiethane-2,1-diyl)bis(5-methoxy-4,7-dioxo-4,7-dihydro-1,3-benzothiazole-2-carboxamide) in solution in 300 ml of anhydrous ethanol. The reaction mixture is stirred at 60° C. for 4 hours then the solvent is evaporated off under reduced pressure. The residue is purified on a silica column (eluent: methanol in dichloromethane: gradient of 0 to 20% over 30 minutes then for 15 minutes with 20% of methanol in dichloromethane) and 12 mg (yield=5%) of expected compound is obtained in the form of a red powder.

Provenance & Evidence