[4-(4-Acetylpiperazin-1-yl)-3-methylphenyl]amine → 5-Chloro-6-(morpholin-4-yl)pyridin-3-amine

HRID 1713791Notes

Reaction equation

HRID 1713791 reaction equation
C(N1CCN(C2C=CC(N)=CC=2C)CC1)(=O)C.[Cl:18][C:19]1[C:20]([N:28]2[CH2:33][CH2:32][O:31][CH2:30][CH2:29]2)=[N:21][CH:22]=[C:23]([N+:25]([O-])=O)[CH:24]=1>>[Cl:18][C:19]1[CH:24]=[C:23]([NH2:25])[CH:22]=[N:21][C:20]=1[N:28]1[CH2:29][CH2:30][O:31][CH2:32][CH2:33]1

Participants

3

Reactant 2

HCID 5311936[4-(4-Acetylpiperazin-1-yl)-3-methylphenyl]amineHCID 594643324-(3-Chloro-5-nitropyridin-2-yl)morpholine

Product 1

HCID 594640685-Chloro-6-(morpholin-4-yl)pyridin-3-amine

Procedure

The title compound was prepared by the general procedure of Intermediate 36 using 4-(3-chloro-5-nitro-pyridin-2-yl)-morpholine.

Sources & evidence

ORD record
ord-21bec706ff6e4001b4fd477292737273
Source dataset
uspto-grants-2010_09
Patent number
US07795283B2

Reaction notes

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