HCID 59464177, compound → HCID 59464297, compound

HRID 1713866Notes

Reaction equation

HRID 1713866 reaction equation
[NH:1]([C:3](=[O:24])[C:4]([NH:6][C:7]1[CH:12]=[CH:11][C:10]([C@H]2CC[C@H](CC(OC)=O)CC2)=[CH:9][CH:8]=1)=[O:5])[NH2:2].COC(=O)C(NC1C=CC([S:37]([C:40]([CH3:46])([CH3:45])[C:41]([O:43][CH3:44])=[O:42])(=[O:39])=[O:38])=CC=1)=O>>[NH:1]([C:3](=[O:24])[C:4]([NH:6][C:7]1[CH:8]=[CH:9][C:10]([S:37]([C:40]([CH3:46])([CH3:45])[C:41]([O:43][CH3:44])=[O:42])(=[O:39])=[O:38])=[CH:11][CH:12]=1)=[O:5])[NH2:2]

Participants

3

Reactant 2

HCID 59464177HCID 59464177, compoundHCID 178500682HCID 178500682, compound

Product 1

HCID 59464297HCID 59464297, compound

Procedure

The procedure described for Intermediate 43 (part iv) was followed starting with methyl 2-[(4-{[methoxy(oxo)acetyl]amino}phenyl)sulphonyl]-2-methylpropanoate to give the title compound; 1H NMR δ 1.56 (s, 6H), 3.67 (s, 3H), 4.77 (s, 2H), 7.77 (d, 2H), 8.11 (d, 2H); MS m/e (M+Na)+ 366.

Sources & evidence

ORD record
ord-ce64c1f17cc547b3a3fcd0c190e8ab20
Source dataset
uspto-grants-2010_09
Patent number
US07795283B2

Reaction notes

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