HuagongsheHuagongshe Chemistry Print Report · For research reference only
[4-(4-Acetylpiperazin-1-yl)-3-methylphenyl]amine → 3,5-Dichloro-4-(morpholin-4-yl)aniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | [4-(4-Acetylpiperazin-1-yl)-3-methylphenyl]amine | HCID 5311936 | — |
| Reactant | 4-(2,6-Dichloro-4-nitrophenyl)morpholine | HCID 12661502 | — |
| Product | 3,5-Dichloro-4-(morpholin-4-yl)aniline | HCID 12661503 | — |
Reaction Steps
Following the general procedure of Intermediate 36 using 4-(2,6-dichloro-4-nitrophenyl)morpholine (prepared as described in J. Med. Chem., 1980, 23(10), 1083) the title compound was obtained; 1H NMR δ 3.01 (4H, t), 3.64 (4H, t), 5.50 (1H, broad s), 6.57 (2H, s); MS m/e MH+ 247.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07795283B2 |
| Source dataset | uspto-grants-2010_09 |
| ORD ID | ord-c597767fc5df43c4a1ca3e002b1ca0bf |
| Source note | uspto-grants-2010_09 |