Methyl chloroglyoxylate → HCID 178501860, compound

HRID 1713885Notes

Reaction equation

HRID 1713885 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([C@H:8]2[CH2:13][CH2:12][C@H:11]([CH2:14][NH:15][C:16](=[O:22])[O:17][C:18]([CH3:21])([CH3:20])[CH3:19])[CH2:10][CH2:9]2)=[CH:4][CH:3]=1.Cl[C:24](=[O:29])[C:25]([O:27][CH3:28])=[O:26].N1(C2C=CC(NC(=O)C(OC)=O)=CC=2)CCOCC1>>[C:18]([O:17][C:16]([NH:15][CH2:14][C@H:11]1[CH2:10][CH2:9][C@H:8]([C:5]2[CH:4]=[CH:3][C:2]([NH:1][C:24](=[O:29])[C:25]([O:27][CH3:28])=[O:26])=[CH:7][CH:6]=2)[CH2:13][CH2:12]1)=[O:22])([CH3:19])([CH3:21])[CH3:20]

Participants

4

Reactant 3

HCID 79846Methyl chloroglyoxylateHCID 59464311HCID 59464311, compoundHCID 178453586HCID 178453586, compound

Product 1

HCID 178501860HCID 178501860, compound

Procedure

Prepared from tert-butyl {[trans-4-(4-aminophenyl)cyclohexyl]methyl}carbamate and methyl chlorooxoacetate by method described for Intermediate 1, method D3.

Sources & evidence

ORD record
ord-ae9787efea2c4216ab0b515772167acf
Source dataset
uspto-grants-2010_09
Patent number
US07795283B2

Reaction notes

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