Dimethyl Sulfide → HCID 68506720, compound

Participants

Reaction Steps

To a solution of methyl 13-cyclohexyl-5-[2-(dimethylamino)ethyl]-6-oxo-4,5,6,7-tetra hydrofuro[3′,2′:6,7][1,4]diazocino[1,8-a]indole-10-carboxylate in THF (0.08 M), 10 eq of BH3.Me2S (2 M sol. in THF) were added and the mixture was stirred at RT for 2 h. The solution was carefully quenched by adding 1.25 M HCl in MeOH until effervescence subsided. Then the volatiles were driven off by boiling the mixture to dryness. The crude residue was used directly in the next step; MS (ES+) m/z 450 (M+H)+.

Provenance & Evidence