HCID 16117546, compound → HCID 16117683, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of cis-3-benzyl-8-bromo-6-methyl-1,2,3,4,4a,9a-hexahydro-3-aza-fluoren-9-one (50 mg, 0.14 mmol) in MeOH (3.0 mL) was added Pd(OH)2 (10.0 mg, 20 wt %). The reaction mixture was stirred at 20° C. for 15 h under H2 atmosphere, filtered through celite and concentrated in vacuo. The residue was chromatographed in silica gel column (CH2Cl2/MeOH 95/5) to give the title compound (20 mg, 0.099 mmol): MS (ES) 202.2 (M+H).

Provenance & Evidence